Overview
IMB’s Core Facilities are hosting a TechTalk on Tuesday, October 14 at 15:00 in IMB’s Seminar Room (2nd floor).
Ilias Zarguit (Business Development Scientist at 1NA) will present on
"High-Throughput Single-Molecule Analysis of DNA-Protein Interactions using DNA Curtains."
Coffee and cake will be served after the talk. All are welcome to attend, but please pre-register for this free event here or by scanning the QR code on the flyer.
Abstract:
DNA curtains are a high-throughput single-molecule approach that enables simultaneous visualization of thousands of DNA-protein interactions, revealing statistically relevant single-molecule level insights. DNA molecules are aligned on nanofabricated barriers within a microfluidics flow cell, allowing real-time observation of dynamic processes such as DNA replication, and repair. 1NA's DNA curtains flow cell addresses key barriers of implementation by applying semiconductor manufacturing practices to the nanofabrication of the barriers. Applications include quantifying DNA-protein kinetics, mapping interaction heterogeneity, or screening small molecule interactions.
