The Institute of Molecular Biology (IMB)

Welcome to IMB! We are a modern research centre that brings together leading scientists from all over the world. Our researchers tackle ambitious projects at the interface of epigenetics, genome stability, ageing & RNA biology.

About us
Who we are, where we are & what we do...
Research
Our scientists & what they are working on...
Core Facilities
State-of-the-art technologies & services...
Students & Postdocs
Training programmes we offer junior researchers...
Seminars & Events
Conferences, meetings, workshops & more...
Careers
Current opportunities at IMB...

The grant will fund his work developing techniques to visualise proteins at nanometer-level resolution inside living cells in real-time.

The award recognises Laura's research into the mechanisms that activate mRNA translation at the beginning of embryonic development.

The conference covered double-strand breaks, chromatin dynamics, replication stress, and age-related diseases and therapies.

13 Aug 2026
Seminar
Integrating Mitochondrial Resilience: From Subcellular Stress Signaling to Systemic Aging
Dr Ye Tian
14 Aug 2026
Seminar | Ad-hoc Seminar
Cap-binding proteins regulate both repression and activation of germline mRNA translation
Prof. Brett Keiper
19 Aug 2026
Seminar | IMB Seminar
Single Cell and Regulatory Genomics of Blood Formation
Dr Lars Velten
19 Aug 2026
Seminar | GenEvo Seminar
Enhancers in Flux Mapping DNA Methylation During Differentiation
Dr Maxim Greenberg
07 Sep - 09 Sep 2026
Meeting & Symposium
RNA Modification and Processing
5th Symposium on Nucleic Acid Modifications
16 Sep 2026
Seminar | 4R-RTG R-loop Club
Dominant mutational scanning of DNA repair proteins to guide mechanistic insights and inhibitor discovery
Dr Peter Stirling

Access the full IMB events calendar by clicking here

Recent Publications

Aug 2026 | Int J Food Sci Nutr | Vieira-Silva
Modified homogalacturonan-rich citrus pectin as potential next-generation prebiotics.
Jul 2026 | Nat Struct Mol Biol | Luck
Variant characterization in the intrinsically disordered human proteome.
Jul 2026 | Nat Commun | Ulrich
Mechanisms of MCM2–7 helicase activation and initial DNA melting at near base-pair resolution.
Jul 2026 | J Am Chem Soc | Lemke
Bis-tetrazine fluorogenic (silicon)-rhodamine dyes for live-cell labeling.
Jul 2026 | Adv Sci (Weinh) | Dormann | Stelzl | Lemke
A phosphorylation-induced micellization switch in the low-complexity domain of TDP-43.
Jul 2026 | Adv Sci (Weinh) | Wittmann
Current challenges of transcription compartmentalization research.
Jul 2026 | EMBO J | Dormann
FUS controls muscle differentiation through phase separation-mediated recruitment of the…
Jul 2026 | Adv Sci (Weinh) | Lemke
A unifying thermodynamic model for phase separation and aging of biopolymers.
Jul 2026 | Aging Cell | Schick | Baumann | Tüscher
Interplay of the ENS and microbiota with murine gut epithelium-derived organoids in aging.
Jun 2026 | Nat Commun | Beli
Systematic discovery of UFM1 receptors reveals a regulatory module in DNA repair directing…

A centre for basic & clinical research on ageing & age-related disease
with Mainz University & its Medical Center, the Leibniz Institute for Resilience Research & TRON
A joint initiative on the mechanisms underlying robustness & longevity
with groups at Mainz University
A joint PhD programme to discover new ways to understand & treat age-related diseases
with Mainz University & its Medical Center
A joint PhD programme to understand why diseases are more common in old age and how we can age healthily
with Helmholtz Munich, the German Center for Neurodegenerative Diseases (DZNE), the University Medical Center Hamburg-Eppendorf, Leipzig University, Greifswald University Hospital, and Mainz University's Medical Center
The largest network on DNA repair & genome stability in Germany
with groups in Mainz, Darmstadt, Frankfurt & Munich
An initiative bridging the polymer & life sciences to understand biological processes such as ageing
with Mainz University, its Medical Center & the Max Planck Institute for Polymer Research
IMB’s flagship PhD training programme on epigenetics, genome stability & ageing
with Mainz University & its Medical Center
A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience
with groups from Mainz University & its Medical Center
A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan
with Mainz University’s Faculty of Biology

News

Edward Lemke awarded an ERC Advanced Grant

Laura Lorenzo-Orts awarded Early Career Research Award by the Biochemical Society

DNA repair experts gather in Mainz for landmark conference

Upcoming Events

13 Aug 2026

14 Aug 2026

19 Aug 2026

19 Aug 2026

07 Sep - 09 Sep 2026

16 Sep 2026

Joint Research Initiatives

A centre for basic & clinical research on ageing & age-related disease

A joint initiative on the mechanisms underlying robustness & longevity

A joint PhD programme to discover new ways to understand & treat age-related diseases

A joint PhD programme to understand why diseases are more common in old age and how we can age healthily

The largest network on DNA repair & genome stability in Germany

An initiative bridging the polymer & life sciences to understand biological processes such as ageing

IMB’s flagship PhD training programme on epigenetics, genome stability & ageing

A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience

A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan