Deciphering the molecular basis of rapid antidepressant action

Research website

Positions held

  • Since 2020: Group Leader, Leibniz Institute for Resilience Research (LIR), Mainz
  • Since 2016: Member, Steering Committee, SFB 1193 "Neurobiology of Resilience"
  • Since 2014: Principal Investigator, Deutsches Resilienz-Zentrum Mainz
  • Since 2014: Professorship (W2) in Translational Psychiatry, Johannes Gutenberg University (JGU), Mainz
  • 2004 - 2013: Head, Independent Research Group Molecular Stress Physiology (MPI of Psychiatry, Munich)
  • 2004 - 2013: Minerva Program (Professorship Award/W2 for outstanding female scientists) from the MPI for the Advancement of Science
  • 2004 - 2007: Assistant Medical Director, Open Psychiatric Ward (Oberärztin)
  • 2003: Board certification, Psychiatry (Fachärztin f. Psychiatrie u. Psychotherapie)
  • 1997: Visiting scientist at the Netherlands Institute for Brain Research, Amsterdam, The Netherlands (Supervisor: Prof. Dr. D.F. Swaab)
  • 1996 - 2003: Residency in Psychiatry and Neurology, clinical training (MPI of Psychiatry, Munich)
  • 1996 - 2003: Postdoctoral Researcher, Molecular Neurogenetics, MPI of Psychiatry, Munich (Prof. Dr. W. Wurst)
  • 1996: Postdoctoral Fellow, Dep. of Neuropathology, University of Bonn Medical Center (Supervisor: Prof. Dr. O.D.Wiestler)


2004: Privatdozentin (Habilitation); Venia Legendi in Psychiatry and Psychotherapy, Ludwig Maximilian University Munich
1996: M.D. degree award, Institute of Neuropathology, University of Bonn (Prof. Dr. O.D. Wiestler)

Selected publications by Marianne Müller

an der Kooij MA, Jene T, Treccani G, Miederer I, Hasch A, Voelxen N, Walenta S, Müller MB (2018) Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory. Proc Natl Acad Sci U S A, 115(43):E10187-E10196 Link

Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, Uhr M, Holsboer F, Sillaber I, Binder EB, Müller MB (2017) Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. PLoS Biol, 15(12):e2002690 Link

vvan der Kooij MA, Masana M, Rust MB, Müller MB (2016) The stressed cytoskeleton: How actin dynamics can shape stress-related consequences on synaptic plasticity and complex behavior. Neurosci Biobehav Rev,  62:69-75 Link

Müller MB, Zimmermann S, Sillaber I, Hagemeyer TP, Deussing JM, Timpl P, Kormann MS, Droste SK, Kühn R, Reul JM, Holsboer F, Wurst W (2003) Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress. Nat Neurosci, 6(10):1100-7 Link